Program & Speakers

Thursday, December 5^th | Day 1

8.00 am - 9.00 am Registration

9.00 am - 9.30 am Welcome Ceremony

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9.30 am - 10.50 am Session 1: Refinement 

(Chair: Branko Zevnik, Cologne)

Stephanie Krämer (Giessen) - "Expanding the Culture of Care in animal research"

Daniel Segelcke (Muenster) - "Innovative Approaches to Identifying Behavioral Markers of Animal Welfare in Rodent Models: Advancing 3R Principles through AI and Machine Learning”

Susanne Wiemann (Bielefeld) - "Oral Application of Tamoxifen in Transgenice Mice"

Dirk Isbrandt (Cologne) - "3R in neurophysiology and experimental epilepsy research"

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10.50 am - 11.10 am Coffee Break

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11.15 am - 1.00 pm Session 2: New Thinking in 3Rs 

(Chair: Marieta Toma, Bonn)

Kim Wever (Nijmegen) -  "Dealing with image duplications in animal research publications"

Steven Talbot (Hannover) - "Improving Laboratory Animal Welfare with Advanced Data Science Methods"

Fernando Gonzalez Uarquin (Mainz)  - "Internal communication in animal facilities for 3R progress"

Elisabeth Jurack (Bonn) - "Does understanding the 3R principle help to improve the acceptance of animal experiments? A representative survey across Germany"

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1.00 pm - 2.00 pm Lunch Break

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2.00 pm - 3.20 pm Session 3: Selected short talks from submitted abstracts 

(Chair: Christine Hartmann, Muenster)

Inês Cabrita (Cologne) - Kidney Organoids: Remarkable Tissues, but Not True Mini-Kidneys

Johanna Maria Hölken (Düsseldorf) - Incorporating immune cell surrogates into a full-thickness tissue equivalent of human skin to characterize dendritic cell activation

Katrin Becker (Bonn) - Application of structure equation models to reduce animal numbers in animal experiments

Sven Fengler (Bonn) - Human iPSC-derived brain endothelial microvessels in a standardized microphysiological system as blood-brain barrier model for drug permeability screens

Nora Rautenberg (Cologne) - Transcranial Direct Current Stimulation (tDCS) in Awake Mice: a flexible model to foster regeneration in various models of neurological disorders

Leonie Tix (Aachen) - Matching suitable lab animals to private pet owners - a key to success

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3.20 pm - 4.20 pm Poster Session (odd numbers) & Coffee Break

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4.20 pm - 5.40 pm Session 4: Reduction 

(Chair: Matthias Schmidt, Bochum)

Kalliopi Pitarokoili (Bochum) -  "Marker of neurodegeneration, neuroprotection and neuroinflammation in cell cultures"

Anna Stettner (Bonn) - "Using the CAM Assay to investigate the behavior of endothelial-like cells in a 3D tumor model"

Barbara Grüner (Essen) - "DNA Barcoding as a means to reduce and refine in vivo drug testing in cancer”

Julia Steitz (Aachen) & Alexandra Bannach-Brown (Berlin) - "Development of a Systematic Online Living Evidence Summary (SOLES) for Animal Models testing Targeted Therapies against Cancer"

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5.40 pm - 5.50 pm Wrap-up Day 1

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From 7.30 pm and on Get-Together at Tivoli Business & Event Bereich in Aachen, Germany
 

Friday, December 6^th | Day 2

8.30 am - 9.00 am Registration

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9.00 am - 10.30 am Session 5: Keynote Lecture 

(Chair: René Tolba, Aachen)

Peter Bollen (Copenhagen) - "Trends and developments within the 3Rs in Denmark"

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10.30 am - 11.40 am Poster Session (even numbers) & Coffee Break

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11.40 am - 1.00 pm Session 6: Replacement 

(Chair: Björn Spittau, Bielefeld)

Saif-Eldin Abedellatif (Bonn) - “Melanoma Brain Metastases Patient-Derived Organoids: An In Vitro Platform for Drug Screening”

Henner Koch (Aachen) - "Human Organotypic Brain Slice Cultures: A Versatile Model System For Neurological Disease"

Florian Groeber-Becker (Düsseldorf) - "In vitro epithelial Models: At the crossroads between Biology - Engineering and Material Science" 

Lena Thiebes (Aachen) - "Modelling the Human Airway Mucosa – A sophisticated In Vitro System for Airway Research" 

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1.00 pm - 1.15 pm Wrap-up and Closing Remarks

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1.30 pm - 3.00 pm 3R-Network-Meeting (only for 3R-Centers)