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The workshop began with a theoretical part led by experts Alina Omerbasic-Schiliro and Frank Dietrich from HHU Düsseldorf. They gave a comprehensive introduction to the basics of ethics and encouraged participants to reflect on the role of ethics in scientific research, methods of ethical analysis and historical perspectives on the ethics of the human-animal relationship. It became clear that ethics are not just rules, but rather an entire framework. It makes an assessment of moral consequences possible, especially in areas where ethical considerations are complex and difficult to decide.

In the first part of the day, attendees looked at the different frameworks that guide ethical decisions in research with animals. It was discussed that ethicists play an important role in analyzing moral issues, especially in complex societal discussions. Another central question addressed whether all animals and humans are entitled to moral consideration, regardless of stage of development, ability or species. This consideration has significant implications for animal and medical ethics. The workshop also emphasized the 3Rs principle (Replacement, Reduction, Refinement). From a consequentialist perspective, animal experimentation ethics can be considered justifiable if the expected benefits, such as potential medical breakthroughs, outweigh the suffering of the animals and no suitable alternatives exist. However, this approach requires a combination of ethical and scientific expertise in order to assess factors such as the ability of animals to suffer, the reliability of alternative methods and the scientific knowledge value.

In the afternoon, the participants were able to work on case studies themselves. The case studies presented practical scenarios from drug development, teaching and training in which animal experiments are to be used. The group then debated the pros and cons in two small groups.  The case studies were deliberately carefully selected so as not to provide clear-cut answers. Instead, they challenged the participants to confront the complex decisions that researchers have to make in ethically challenging situations. The discussions encouraged participants to engage in deep reflection and lively exchange about ethical conduct and emphasized the importance of applying ethical principles in practice.

At the end of the workshop, the participants agreed to further promote ethical standards in research. The workshop highlighted the need for continuous dialog and the importance of a flexible ethical framework that adapts to new developments. The 3R Workshop NRW provided a valuable opportunity to exchange ideas, which was made possible by the commitment of the speakers, active participation and organization. This collaboration reinforces the notion that responsible science requires a constant review and strengthening of ethical standards.